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BCHM Biochemistry( Chemical and Life Sciences)The College of Chemical and Life Sciences enforces course prerequisites. Students who do not meet the course prerequisites will be administratively dropped from the course. Registration in course sections which begin with "SEF*" are restricted to Post-Baccalaureate students who enroll through the Science in the Evening Program in the College of Chemical and Life Sciences. Please note that this class is charged at the regular part-time tuition rate (on a per credit basis), even for full- time students. To register or to learn more about the Science in the Evening program, you must contact the Life Sciences Outreach and Special Programs Office at (301) 405-6892.
BCHM461
Biochemistry I;
(3 credits)
Grade Method: REG/P-F/AUD.
BCHM462 Biochemistry II; (3 credits) Grade Method: REG/P-F/AUD. Prerequisite: BCHM461. A grade of C or better in the prerequisite is required for Life Science majors and recommended for all students. Not open to students who have completed BCHM463. Credit will be granted for only one of the following: BCHM462 or BCHM463. A continuation of BCHM 461. Metabolic pathways and metabolic regulation, energy transduction in biological systems, enzyme catalytic mechanisms. BCHM463 Biochemistry of Physiology; (3 credits) Grade Method: REG/AUD. Prerequisite: {CHEM271 and CHEM272} or {CHEM276 and CHEM277} or {CHEM113 and CHEM241 and CHEM242}. A grade of C (2.0) or better is required in all prerequisites. Not open to students who have completed BCHM461 or BCHM462. Credit will be granted for only one of the following: BCHM463 or {BCHM461 or BCHM462}. A one-semester introduction to general biochemistry. A study of protein structure, enzyme catalysis, metabolism, and metabolic regulation with respect to their relationship to physiology. BCHM464 Biochemistry Laboratory; (3 credits) Grade Method: REG/P-F/AUD. Prerequisite: BCHM461 or BCHM463. A grade of C or better in the prerequisite is required for Life Science majors and recommended for all students. Corequisite: BCHM465. BCHM, CHEM and Nutritional Sciences majors have first priority, followed by other life science majors. Biochemical and genetic methods for studying protein function. Site-directed mutagenesis and molecular cloning, protein purification, enzyme activity assays, computer modeling of protein structure. Students must pay a $40.00 Laboratory Materials fee. BCHM465 Biochemistry III; (3 credits) Grade Method: REG/P-F/AUD. CORE Capstone (CS) Course. Prerequisite: BCHM461 or BCHM463. A grade of C or better in the prerequisite is required for Life Science majors and recommended for all students. Recommended: BCHM462. CORE Capstone (CS) Course. An advanced course in biochemistry. Biochemical approach to cellular information processing. DNA and RNA structure. DNA replication, transcription, and repair. Translation of mRNA to make proteins. BCHM671 Protein Chemistry and Enzymic Catalysis; (3 credits) Grade Method: REG/AUD. Prerequisite: BCHM 416 or equivalent. Principles of protein structure, folding, and function, experimental characterization of structure, active sites, enzyme mechanisms and kinetics. BCHM673 Regulation of Metabolism; (3 credits) Grade Method: REG/AUD. Prerequisite: BCHM 462 or BCHM 463 or equivalent. Intracellular milieu, compartmentation, metabolic and enzymic approaches to identifying control points, regulation by covalent modification of enzymes, metabolic disorders. BCHM674 Nucleic Acids; (3 credits) Grade Method: REG/AUD. Prerequisite: BSCI 410 or equivalent. Chemistry of nucleotides and polynucleotides, sequencing and organization of genomes, experimental methods. DNA replication, repair, and recombination. RNA synthesis and processing, regulation of gene expression. BCHM699 Special Problems in Biochemistry; (1-6 credits) Grade Method: REG/AUD. Individual Instruction course: contact department or instructor to obtain section number. Open only to non-thesis M.S. degree candidates. BCHM799 Master's Thesis Research; (1-6 credits) Grade Method: REG. Individual Instruction course: contact department or instructor to obtain section number. BCHM889A Seminar: Biochemistry; (1 credit) Grade Method: REG/AUD. BCHM889C (PermReq) Seminar: Allostery in DNA Binding; (1 credit) Grade Method: REG/AUD. BCHM889D (PermReq) Seminar: Enzymology Recombination; (1 credit) Grade Method: REG/AUD. BCHM889E (PermReq) Seminar: Biological Mass Spectrometry; (1 credit) Grade Method: REG/AUD. BCHM889F (PermReq) Seminar: Antimicrobial Peptides; (1 credit) Grade Method: REG/AUD. BCHM889I (PermReq) Seminar: Cancer Susceptibility Genes: Structures and Mechanisms; (1 credit) Grade Method: REG/AUD. BCHM889J (PermReq) Seminar: Nucleic Acid Structures; (1 credit) Grade Method: REG/AUD. BCHM889K (PermReq) Seminar: Protein Folding; (1 credit) Grade Method: REG/AUD. BCHM889M Seminar: Modern Methods in NMR and Structural Biology; (1-3 credits) Grade Method: REG/AUD. BCHM889P (PermReq) Seminar: Structure and Reactivity of Biopolymers; (1 credit) Grade Method: REG/AUD. BCHM898 Pre-Candidacy Research; (1-8 credits) Grade Method: REG. Individual Instruction course: contact department or instructor to obtain section number. BCHM899 (PermReq) Doctoral Dissertation Research; (6 credits) Grade Method: REG. Individual Instruction course: contact department or instructor to obtain section number.
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