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BIOE Bioengineering ( The A. James Clark School of Engineering)BIOE120 Biology for Engineers; (3 credits) Grade Method: REG/P-F/AUD.For BIOE majors only. A combination of lectures and discussions covering biology from a utilization perspective, and lectures on illustrative mathematical models that capture the essences of characteristics of living entities. The biology material will focus on: distinguishing engineering from biological science, principles form the sciences applicable to biology, typical biological responses to environmental stimuli, scaling of biological responses, and different means to utilize living entities. BIOE121 Biology for Engineers Laboratory; (1 credit) Grade Method: REG/P-F/AUD. For BIOE majors only. This course will build on the material covered in BIOE120. Experiments conducted in this laboratory course will cover topics such as biomechanical principles, biochemical methods, genetics and selection, scaling, microcosm interactions, human factors and imaging. BIOE340 Modeling Physiological Systems and Lab; (4 credits) Grade Method: REG/P-F/AUD. Prerequisite: BIOE120 and BIOE121. Credit will be granted for only one of the following: BIOE340 or (BSCI440 and BSCI441). Topics covered will include cell and general physiology, membrane physiology, blood cells and clotting, circulation, metabolism, respiration, and the nervous system. A lab component will also be included. BIOE399 (PermReq) Independent Study in Bioengineering; (1-3 credits) Grade Method: REG/P-F/AUD. Individual Instruction course: contact department or instructor to obtain section number. Prerequisite: Permission of department. BIOE430 Introduction to Cellular Computing and Synthetic Biology; (1 credit) Grade Method: REG/P-F/AUD. Senior standing. Credit will be granted for only one of the following: BIOE430 or BIOE630. Computational modeling of biological systems and the engineering of synthetic biochemical networks. The emerging field of synthetic biology and its relevance to the study of natural systems will be explored. Topics covered will include deterministic and stochastic modeling of gene regulatory networks, the study of molecular switches, synthetic oscillators, feedback and autoregulatory networks and cell-cell communication systems. BIOE468M Selected Topics in Bioengineering: Cell Motility; (3 credits) Grade Method: REG/P-F/AUD. Also offered as BIOE689M and ENCH468O. BIOE482 Analysis of Bioenergy Systems; (3 credits) Grade Method: REG/P-F/AUD. Prerequisite: CHEM231, CHEM232, and ENME232. Combines topics from biofuels (some of which are renewable/sustainable) and biofuel cells. Emphasizes both engineering and biological analysis while including a practical perspective based on specific examples from the current literature. Ethanol from corn and sugar cane; gasoline from biomass; use of cullulosic biomass; enzymatic and microbial biofuel cells. BIOE602 Cellular and Tissue Biomechanics; (3 credits) Grade Method: REG/AUD. Introduction to the fundamentals of biomechanics including force analysis, mechanics of deformable bodies, stress and strain, multiaxial deformations, stress analysis, and viscoelasticity. Biomechanics of soft and hard tissues. BIOE603 Electrophysiology of the Cell; (3 credits) Grade Method: REG/AUD. Introduction to the electrophysiology of the cell membrane. Development of mathematical models of different types of ionic membrane currents and fluid compartment models, culminating in the development of functional whole-cell models for neurons and muscle (cardiac, skeletal and smooth muscle) cells. Characterization of volume conductor boundary value problems encountered in electrophysiology consisting of the adequate description of the bioelectric current source and the volume conductor (surrounding tissue) medium. BIOE605 Laboratory Rotations I; (1 credit) Grade Method: REG. For BIOE majors only. Provides the opportunity to experience different laboratory environments. Students gain exposure to graduate research, learn a wide variety of laboratory and/or computational techniques, become familiar with Bioengineering program faculty, and develop insight on personal research interests and direction. Laboratory rotations are required in Fall and Spring of the first year of the Ph.D. Program. BIOE605: Laboratory Rotations I will be held in the Fall semester. BIOE606: Laboratory Rotations II will be held in the Spring semester. BIOE608 Bioengineering Seminar Series; (1 credit) Grade Method: REG/AUD. For BIOE majors only. BIOE630 Introduction to Cellular Computing and Synthetic Biology; (1 credit) Grade Method: REG/AUD. Credit will be granted for only one of the following: BIOE430 or BIOE630. Computational modeling of biological systems and the engineering of synthetic biochemical networks. The emerging field of synthetic biology and its relevance to the study of natural systems will be explored. Topics covered will include deterministic and stochastic modeling of gene regulatory networks, the study of molecular switches, synthetic oscillators, feedback and autoregulatory networks and cell-cell communication systems. BIOE645 Advanced Engineering Start Up Ventures; (3 credits) Grade Method: REG/AUD. Covers principles and practices important to engineering startup ventures, especially those involving bioengineering and medical device enterprises, and includes the preparation of business plans and tools used to obtain funding. This course will be taught in the Maryland Technology Enterprise Bldg. BIOE689J Special Topics in Bioengineering: Use of Genomics and Proteomics in Infectious Disease; (3 credits) Grade Method: REG. BIOE689M Special Topics in Bioengineering: Cell Motility; (3 credits) Grade Method: REG. Also offered as BIOE468M and ENCH468O. BIOE689N Special Topics in Bioengineering: Bionanotechnology: Physical Principles; (3 credits) Grade Method: REG. Also offered as ENCH648N. BIOE799 Master's Thesis Research; (1-6 credits) Grade Method: REG/S-F. Individual Instruction course: contact department or instructor to obtain section number. BIOE898 Pre-Candidacy Research; (1-8 credits) Grade Method: REG/S-F. Individual Instruction course: contact department or instructor to obtain section number. BIOE899 (PermReq) Doctoral Dissertation Research; (6 credits) Grade Method: REG/S-F. Individual Instruction course: contact department or instructor to obtain section number.
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